Top 10 AI Prompts and Use Cases and in the Healthcare Industry in Topeka

By Ludo Fourrage

Last Updated: August 30th 2025

Healthcare professional using AI on a tablet in a Topeka clinic, illustrating AI prompts and use cases.

Too Long; Didn't Read:

For Topeka healthcare leaders: pilot measurable AI prompts - documentation (DAX Copilot: ~7 min saved, ~50% doc reduction), scribing (Sully.ai: 15→1–5 min, up to 90% burnout drop), readmission models (16.5% baseline), fraud detection (≈30% fewer frauds) - start small with governance.

For healthcare leaders in Topeka, AI prompts and realistic use cases aren't abstract tech trends - they're tools for trimming paperwork, improving outreach and protecting patient equity while local public health groups build policy guardrails: the Kansas Health Institute has been leading a statewide AI roadmap effort to help counties adopt GenAI responsibly (Kansas Health Institute statewide AI roadmap for public health), and reporting from the Kansas City area shows hospitals using AI to reduce administrative burden and even cut discharge delays to well under two hours (Kansas City hospitals using AI to reduce administrative burden and discharge delays).

Practical, prompt-writing training can close the gap between promise and safe practice - programs like the AI Essentials for Work bootcamp teach nontechnical staff how to write effective prompts and govern GenAI in daily operations (AI Essentials for Work bootcamp at Nucamp: learn to write effective AI prompts for work), a small, practical step that helps Topeka providers pilot tools without risking patient trust.

BootcampLengthEarly bird costIncludesRegister
AI Essentials for Work 15 Weeks $3,582 AI at Work: Foundations; Writing AI Prompts; Job Based Practical AI Skills Register for the AI Essentials for Work bootcamp at Nucamp

“Because, unfortunately,” said Lindsey Jarrett, vice president of ethical AI at Kansas City's Center for Practical Bioethics, “no one's really telling them they have to.”

Table of Contents

  • Methodology: How We Selected the Top 10 AI Prompts and Use Cases
  • Nuance DAX Copilot: Clinical Documentation Automation Prompt
  • Sully.ai + Parikh Health Agent: Charting and Physician Burnout Reduction Prompt
  • Insilico Medicine: Drug Discovery and Clinical Trial Optimization Prompt
  • UnityPoint Health Predictive Analytics: Readmission Reduction Prompt
  • NVIDIA Clara Federated Learning: Synthetic Data and Privacy-Preserving Training Prompt
  • Enlitic: Radiology Prioritization and Triage Prompt
  • Wysa or Woebot Health: On-Demand Mental Health Support Prompt
  • Markovate: Fraud Detection and Claims Processing Prompt
  • Dragon Medical One / Cencora Speech Agent: Voice-Assisted Insurance and Front-Desk Automation Prompt
  • SOPHiA DDM by SOPHiA GENETICS: Genomic Variant Interpretation Prompt
  • Conclusion: Next Steps for Topeka Healthcare Providers - Start Small, Govern Well
  • Frequently Asked Questions

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Methodology: How We Selected the Top 10 AI Prompts and Use Cases

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Selection started with evidence: only prompts and use cases with documented, production‑grade outcomes or replicable pilot metrics made the cut - think examples that cut clinical documentation time by roughly 60% or accelerated discovery timelines by about 70% - so local Topeka teams can see what's likely to move the needle in a community hospital or county health department.

Priority criteria were measurable ROI (short time‑to‑value and clear throughput or cost improvements), real deployments or strong vendor case studies, alignment with the 2025 adoption trends (data analytics, generative AI and LLMs), and fit for mid‑sized/regional systems that face tight budgets and privacy requirements.

Sources used to score candidates included comparative case studies and trend surveys to balance impact versus risk - for instance, broad ROI reviews and concrete system wins informed weighting, while rev‑cycle and scheduling wins illustrated how a single pilot can quickly add cases and revenue for regional providers.

Readers should be able to map each prompt to an operational metric they can track in weeks, not years, and to a governance checklist for safe rollout (detailed AI case study ROI examples: AI case study ROI examples for healthcare, analysis of AI adoption trends in life sciences and healthcare: 2025 AI adoption trends in healthcare and life sciences, and revenue cycle AI outcomes and measurable ROI: revenue cycle AI tools delivering measurable ROI in healthcare).

“If you can't measure it, you can't manage it.” - Peter Drucker

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Nuance DAX Copilot: Clinical Documentation Automation Prompt

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Nuance's DAX Copilot - the Dragon Ambient eXperience now embedded into Epic workflows - is a practical prompt-driven tool Topeka clinics can pilot to cut documentation time and reclaim clinician attention: integrated ambient capture and Dragon dictation create specialty‑specific notes, surface orders and after‑visit summaries, and can pick up multilingual encounters so providers spend less time typing and more time with patients (Nuance and Epic DAX Express integration details).

Microsoft's Dragon Copilot bundles those capabilities into an extensible workspace that cites outcomes like faster throughput, fewer denials, and tools to summarize evidence and clinical encounters for safer decision‑making - it became generally available in the United States in 2025 and is already in wide rollout (Microsoft Dragon Copilot clinical documentation automation overview).

With more than 150 health systems planning deployments, DAX Copilot represents a near‑term, measurable lever for mid‑sized Kansas hospitals to reduce burnout and improve access: even modest savings (roughly seven minutes per visit in case studies) stack up quickly across a clinic schedule, turning paperwork time into extra appointment slots or shorter waitlists (Healthcare Dive coverage of DAX Copilot and Epic integration).

MetricReported ValueSource
Time saved per encounter~7 minutesDictationOne / product outcomes
Documentation time reduction~50%DictationOne / product outcomes
Health systems deploying>150 systemsHealthcare Dive
Example ROI (Northwestern Medicine)112% ROI; 3.4% service‑level increaseMicrosoft outcomes study

“Dragon Copilot is a complete transformation of not only those tools, but a whole bunch of tools that don't exist now when we see patients. That's going to make it easier, more efficient, and help us take better quality care of patients.” - Anthony Mazzarelli, MD

Sully.ai + Parikh Health Agent: Charting and Physician Burnout Reduction Prompt

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For Topeka clinics eyeing quick wins on clinician time and morale, Sully.ai's Parikh Health story reads like a playbook: by integrating an AI agent into the EMR and automating intake, in‑visit scribing and post‑visit tasks, Parikh Health cut charting from roughly 15 minutes to 1–5 minutes per patient, reported a 10x decrease in operations per patient and as much as a 90% reduction in physician burnout - outcomes that translated to faster visits, more appointment capacity and less after‑hours work (Parikh Health Sully.ai implementation case study).

Sully.ai's broader case studies and marketplace listings show consistent gains - clinicians saving multiple daily hours, 100+ organizations deploying the agent, and HIPAA‑compliant EMR integrations - making this a pragmatic prompt-driven use case Topeka teams can pilot to reclaim clinician time and reduce burnout without reworking core clinical systems (Sully.ai case studies and marketplace listings).

MetricReported ValueSource
Charting time per patient15 min → 1–5 minParikh Health case study
Operations per patient10× decreaseParikh Health case study
Physician burnoutUp to 90% decreaseParikh Health case study
Organizations using Sully.ai100+Sully.ai case studies

“Sully.ai is an all-in-one solution, from patient intake to in-visit interactions with patients, as well as aftercare and follow-up. For us physicians, it's a game-changer.” - Neesheet Parikh, DO

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Insilico Medicine: Drug Discovery and Clinical Trial Optimization Prompt

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Insilico Medicine-style in silico drug discovery offers Topeka providers and local biotech partners a way to shrink timelines and costs by letting AI explore chemical space far faster than lab teams alone: generative approaches such as GANs and reinforcement learning can propose novel candidates from a theoretical pool of more than 10^60 pharmacology‑active compounds, then prioritize those with better predicted potency, synthesizability and safety so wet labs focus only on the most promising leads (Wyss Institute AI drug discovery overview).

Reviews of AI in translational medicine underscore real benefits - faster target ID, virtual screening and trial optimization - while flagging data quality, interpretability and regulatory hurdles that local systems must manage (Review of AI applications in precision medicine - translational medicine review).

For community stakeholders in Kansas, the practical “so what” is clear: computational triage can lower the upfront R&D tab and shorten recruitment windows, but pilots must pair these tools with strong privacy and consent safeguards to protect patients and maintain trust (Privacy and consent safeguards for Topeka AI healthcare deployments).

UnityPoint Health Predictive Analytics: Readmission Reduction Prompt

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UnityPoint Health teams in Topeka can turn readmission risk from a nagging metric into an actionable prompt by leaning on proven predictive analytics tactics: studies show roughly one in six discharged high‑risk patients were readmitted within 30 days, and models that fold nursing assessments into early prediction meaningfully improve detection - 45% of top early predictors in a recent JMIR model were nursing variables, with a day‑one Random Forest test AUROC ≈0.62 and a full‑stay CatBoost AUROC ≈0.64 (JMIR study: nursing-inclusive readmission prediction models).

Translating that into a Topeka pilot means building an EHR‑embedded prompt that flags patients with high BMI, abnormal systolic BP, elevated ward‑severity or fall‑risk scores for early case‑management, echoing broader guidance on how predictive scores drive targeted post‑discharge follow‑up in family medicine (MGH IHP: predictive analytics to reduce hospital readmissions).

The payoff is tangible: earlier interventions for the ~16% at risk can shrink avoidable returns and focus scarce care‑coordination resources where they matter most.

MetricValueSource
30‑day unplanned readmission rate16.5%JMIR study
Model 1 (early, RF) test AUROC0.62JMIR study
Model 2 (entire stay, CatBoost) test AUROC0.64JMIR study
Proportion of top early predictors that were nursing variables45%JMIR study

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NVIDIA Clara Federated Learning: Synthetic Data and Privacy-Preserving Training Prompt

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For Topeka health systems wary of sending protected health data offsite, NVIDIA's approach pairs high‑fidelity synthetic imaging with privacy‑first federated learning so hospitals can improve models together without sharing raw records: Project MONAI and MAISI can generate realistic 2D/3D CT “digital twin” images - including up to 127 anatomical classes and disease biomarkers - to fill rare‑disease gaps and expand demographic diversity in training sets (NVIDIA synthetic data generation for healthcare innovation), while Clara Train's federated learning workflow lets each site train locally and only send encrypted model updates to a central server, preserving HIPAA‑level data locality and using tokens and SSL for trust (NVIDIA Clara Train federated learning SDK for healthcare).

The practical upshot for Kansas clinics and regional systems: a mid‑sized hospital can join a multicenter training round and gain models that recognize rare imaging patterns without ever leaving the local network - think dozens of synthesized rare‑tumor scans powering safer, faster detection across the state.

This makes federated CLARA + synthetic data a pragmatic prompt for pilots that balance model quality, speed and patient privacy.

Enlitic: Radiology Prioritization and Triage Prompt

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For Topeka hospitals and regional imaging centers wrestling with staffing gaps and messy PACS metadata, Enlitic offers a pragmatic triage and prioritization prompt that makes studies behave: ENDEX™ standardizes study descriptions, corrects misspellings (yes, it can catch a “CT Brian” typo that would otherwise miss AI processing), and routes urgent cases to the right readers so radiologists see the sickest patients first rather than hunting for the right series at 4:30 a.m.; the result is cleaner worklists, fewer false negatives, and faster throughput that matters when a single overnight CT can change a life.

Enlitic's product pages and its AI‑ready data primer spell out how metadata enrichment, intelligent hanging protocols and automated routing plug into existing PACS/RIS workflows to boost efficiency and create an evidence base for local pilots (Enlitic ENDEX radiology solutions, Enlitic AI-ready data primer for radiology); for Kansas systems the practical payoff is measurable: triage that cuts reading noise so scarce radiology hours are spent where outcomes improve fastest.

MetricReported ValueSource
Faster interpretation>20% fasterEnlitic press release / applied radiology
Improved true positive / reduced false positivesImproved true positives; >10% fewer false positivesEnlitic press release
Chest X‑ray AUC improvement~16% increase vs. human baselineApplied Radiology summary

“Radiologists need to identify thousands of abnormalities across hundreds of image types under time pressure.” - Kevin Lyman, CEO, Enlitic

Wysa or Woebot Health: On-Demand Mental Health Support Prompt

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On-demand chatbots like Wysa and Woebot can give Topeka clinics a practical, always‑on way to broaden behavioral health access where clinicians are scarce: a randomized trial of Wysa in people with arthritis or diabetes showed statistically significant drops in both PHQ‑9 and GAD‑7 scores by week 4 (treatment users improved while controls did not), and in the diabetes subgroup average PHQ‑9 fell from “mild” to “minimal” in just four weeks (Wysa randomized controlled trial (JMIR Formative Research)).

That real‑world accessibility - quiet, private support a patient can open on a smartphone at 2 a.m. - is the vivid “so what”: small symptom gains delivered at scale can prevent deterioration in communities where access is limited.

Caveats matter: interdisciplinary reviewers flag conversational limits, crisis‑management gaps and trust concerns, so these tools are best deployed as adjuncts with escalation pathways and clinician oversight rather than replacements for therapy (Expert analysis of AI-driven mental health chatbots (JMIR)).

For health systems weighing pilots, evaluate user cohorts, privacy safeguards, and blended models like Wysa's hybrid human+AI offering before scaling (Wysa Copilot hybrid human+AI support platform).

MetricTreatment (Wysa) Baseline → Week 4Control Baseline → Week 4Source
PHQ‑9 (depression)8.65 → 5.267.82 → 7.56JMIR Formative Research randomized controlled trial
GAD‑7 (anxiety)7.44 → 4.746.09 → 6.56JMIR Formative Research randomized controlled trial
PSS‑10 (stress)19.00 → 17.06 (no significant change)17.53 → 17.35 (no significant change)JMIR Formative Research randomized controlled trial

Markovate: Fraud Detection and Claims Processing Prompt

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For Topeka payers and mid‑sized hospitals wrestling with thin margins, Markovate's AI‑driven fraud detection and claims automation is a practical prompt to stop wasted payments and speed reimbursements: their writeups show AI that watches billing patterns, flags duplicate or upcoded claims, and links claims to patient and provider networks so investigators see suspicious clusters instead of sifting spreadsheets all night (Markovate AI healthcare fraud detection overview).

Real deployments promise concrete payoffs - case examples include double‑digit drops in fraudulent claims and major speedups in processing - so a Kansas insurer or hospital system can expect faster cash flow and fewer erroneous payouts while protecting local patient trust against medical identity theft.

Pilots also bring practical guardrails: run claims‑triage models in parallel, validate on historical files, and route high‑risk items to human review - catching an anomalous provider pattern early can save thousands and keep scarce county health dollars working for patients, not fraudsters (Markovate AI claims processing solutions).

MetricReported ValueSource
Reduction in fraudulent claims30% (within 6 months)Markovate fraud detection case outcomes
Faster claims processing40% fasterMarkovate fraud detection case outcomes
Processing time reduction (other example)45% reduction in processing timeMarkovate claims processing outcomes

Dragon Medical One / Cencora Speech Agent: Voice-Assisted Insurance and Front-Desk Automation Prompt

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For Kansas clinics looking to shave minutes off every patient interaction, Nuance's Dragon Medical One is a practical engine for voice‑assisted insurance checks and front‑desk automation: the cloud speech platform lets staff dictate into EHR fields, launch apps, and “transfer text” from dictation boxes into forms, while auto‑texts and custom voice commands speed repetitive insurance verifications and prior‑authorization language (Dragon Medical One implementation guidance for clinics).

Real clinics report sizable time savings - well‑tuned Dragon setups and command libraries can cut documentation 25–50% and let teams close notes at the point of care rather than catching up after hours (Dragon Medical One command best practices and efficiency tips).

Practical adoption hinges on training and small hardware choices - simple tips like keeping the microphone about 1–3 inches from the mouth and using specialty auto‑texts dramatically improve accuracy - so a phased pilot in Topeka's outpatient clinics can speed front‑desk throughput without heavy IT overhaul (Dragon Medical One dictation tips from Johns Hopkins).

“I can close my note after seeing a patient and not have this hanging over me.” - Joseph Cofrancesco Jr.

SOPHiA DDM by SOPHiA GENETICS: Genomic Variant Interpretation Prompt

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For Kansas labs and Topeka hospitals aiming to bring precision medicine in‑house without adding a bioinformatics army, SOPHiA DDM™ is a practical genomic‑variant interpretation prompt: the IVDR‑certified, cloud platform collapses variant calling, annotation, prioritization and CAP/CLIA‑ready reporting into a single workflow so difficult questions - oncology targets or rare inherited causes - move from ambiguous send‑outs to actionable reports faster, often spotting challenging signals like Alu insertions, mosaic variants and complex CNVs that traditional pipelines miss; its proprietary UMI tech (CUMIN™) can detect low‑frequency variants down to ~0.5% VAF, a vivid capability that turns one faint signal into a different clinical pathway.

Local labs can use the Enhanced Exome option to replace multiple panels with a single, upgradeable exome workflow, tap the SOPHiA community for shared variant insights, and rely on documented security and compliance to protect patient data - making this a realistic pilot for Topeka systems that need faster turnaround, fewer send‑outs, and tighter privacy controls (SOPHiA DDM genomics platform overview: SOPHiA DDM™ for Genomics platform overview; SOPHiA DDM Enhanced Exome Solutions details: Enhanced Exome Solutions details; privacy and consent safeguards for Topeka AI healthcare deployments: privacy and consent safeguards for Topeka pilots). Metrics summary: Certifications & compliance - IVDR; supports HIPAA, GDPR, ISO/IEC 27001/27017/27018 (source: SOPHiA DDM pages).

Detected variant types - SNVs, Indels, CNVs, fusions, mitochondrial variants, Alu insertions, star alleles, mosaic variants (source: Enhanced Exome Solutions).

Exome gene counts - Clinical Exome: ~6,380 genes; Whole Exome: ~19,425 genes (source: Enhanced Exome Solutions). UMI sensitivity - Down to ~0.5% VAF (CUMIN™) (source: Enhanced Exome Solutions).

Conclusion: Next Steps for Topeka Healthcare Providers - Start Small, Govern Well

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Topeka providers ready to move from curiosity to impact should follow a simple playbook: start small with one measurable pilot, map that pilot to an operational metric, and build governance from day one so lessons scale safely - exactly the advice legal and policy experts recommend when implementing AI in healthcare (Best practices for AI in healthcare).

Prioritize easy wins (claims triage, documentation, scheduling) and validate continuously - industry guides urge clear goals, privacy safeguards and stakeholder feedback to avoid repeating the usability mistakes of prior large IT rollouts (10 best practices for implementing AI in healthcare), and independent reviews show many research tools never reached production, so pragmatic pilots matter.

Invest in people as much as tech: a 15‑week, skills‑focused course like Nucamp's AI Essentials for Work helps nontechnical staff learn prompt writing, governance and practical deployment steps - small training, clearer risk controls, faster local wins (AI Essentials for Work bootcamp at Nucamp).

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Frequently Asked Questions

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What are the most practical AI use cases Topeka healthcare providers should pilot first?

Prioritize measurable, low-risk pilots with quick time-to-value: clinical documentation automation (Nuance DAX/Dragon Copilot), in-visit scribing and charting agents (Sully.ai/Parikh Health), claims triage and fraud detection (Markovate), front-desk/insurance automation (Dragon Medical One/Cencora), and radiology prioritization (Enlitic). These targets have documented production wins, clear operational metrics, and fit mid-sized regional systems.

What measurable metrics can Topeka health systems expect from these pilots?

Expected outcomes from documented case studies include: ~7 minutes saved per encounter and ~50% documentation time reduction (Nuance DAX), charting time reduced from ~15 minutes to 1–5 minutes and large drops in physician burnout (Sully.ai), 30% reduction in fraudulent claims and up to ~40–45% faster claims processing (Markovate), >20% faster radiology interpretation and >10% fewer false positives (Enlitic), and 25–50% cuts in administrative/front-desk documentation time (Dragon Medical One). Use these as baseline targets and validate locally.

How should Topeka organizations manage privacy, governance, and risk when deploying AI?

Adopt governance from day one: run pilots in production-like settings, validate models on historical data, keep human-in-the-loop review for high-risk items, and use privacy-preserving methods where possible (federated learning and synthetic data via NVIDIA Clara/Project MONAI). Follow local/state guidance (e.g., Kansas Health Institute AI roadmap), require HIPAA/compliance assurances from vendors, and map each pilot to a governance checklist that includes consent, audit logs, escalation paths, and continuous monitoring.

Which AI tools support specialty workflows important to Topeka providers (imaging, genomics, drug discovery)?

Specialty tools highlighted include: Enlitic for imaging prioritization and metadata enrichment; SOPHiA DDM for genomic variant interpretation with IVDR certification and UMI sensitivity (~0.5% VAF); NVIDIA Clara federated learning and synthetic imaging to augment rare-disease training without sharing raw PHI; and Insilico Medicine–style in silico discovery for accelerating lead generation and trial optimization. Each offers domain-specific workflows but requires integration, validation, and compliance checks before scaling.

What are recommended next steps and capability-building actions for a Topeka health system ready to pilot AI?

Start small with one measurable pilot tied to an operational metric (e.g., documentation time, readmission risk, claims processing speed); choose a vendor or approach with production evidence; create a governance checklist and human-review pathways; run parallel validation on historical data; and invest in staff capability-building such as a focused prompt-writing and governance course (for example, a 15-week AI Essentials for Work bootcamp) to ensure nontechnical staff can safely operate and scale the tool.

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Ludo Fourrage

Founder and CEO

Ludovic (Ludo) Fourrage is an education industry veteran, named in 2017 as a Learning Technology Leader by Training Magazine. Before founding Nucamp, Ludo spent 18 years at Microsoft where he led innovation in the learning space. As the Senior Director of Digital Learning at this same company, Ludo led the development of the first of its kind 'YouTube for the Enterprise'. More recently, he delivered one of the most successful Corporate MOOC programs in partnership with top business schools and consulting organizations, i.e. INSEAD, Wharton, London Business School, and Accenture, to name a few. ​With the belief that the right education for everyone is an achievable goal, Ludo leads the nucamp team in the quest to make quality education accessible